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NBIP Ireland
Research Office
121 St Stephens Green
Dublin 2
Ireland

nbipadmin@rcsi.ie
+353 1 402 8651



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Project Title: The molecular mechanisms of estrogen induced anti-secretory responses in human bronchus and implications in Cystic Fibrosis.

 

Host Laboratory: Royal College of Surgeons in Ireland, Molecular Medicine Laboratories, Education and Research Centre, Smurfit Building,Beaumont Hospital, Dublin 9.

 

Research Interests: Cell Signalling and Molecular Endocrinology

 

Technical Expertise: Molecular and Cellular Imaging

 

Curriculum Vitae

 

Publications:

Articles:

  • Restoration of chloride efflux by Azithromycin in CF human bronchial epithelial cells (2009) Saint-Criq V, Rebeyrol C, Ruffin M, Guillot L, Jacquot J, Clement A, Tabary O PLoS ONE submitted
  • Pro-inflammatory effect of sodium 4-phenylbutyrate in deltaF508-CFTR lung epithelial cells: Involvement of ERK1/2 and JNK signaling (2008) Roque T, Boncoeur E, Saint-Criq V, Bonvin E, Clement A, Tabary O, Jacquot J J Pharmacol Exp Ther 326(3):949-56
  • Oxidative stress induces extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase in cystic fibrosis lung epithelial cells: Potential mechanism for excessive IL-8 expression (2008) Saint-Criq V, Boncoeur E, Bonvin E, Roque T, Henrion-Caude A, Gruenert DC, Clement A, Jacquot J, Tabary O Int J Biochem Cell Biol 40(3):432-46
  • Cystic Fibrosis Transmembrane Conductance Regulator Controls Lung Proteasomal Degradation and Nuclear Factor- B Activity in Conditions of Oxidative Stress (2008) Boncoeur E, Roque T, Bonvin E, Saint-Criq V, Henrion-Caude A, Bonora M, Clement A, Tabary O, Jacquot J Am J Pathol 172:1184-1194
Abstract Publication:
  • CFTR chloride is necessary to anti-inflammatory effects of Azithromycin in bronchial epithelial cells. Saint Criq V, Ruffin M, Rebeyrol C, Guilot L, Jacquot J, Clement A, Tabary O. Pediatric pulmonology, supplement 32, p.260, 2009
  • Weak anti-inflammatory effects of glucocorticoids on CF bronchial epithelial cells. Rebeyrol C, Guillot L, Saint Criq V, Ray D, clement A, Tabary O, Le Rouzic P. Pediatric pulmonology, supplement 32, p.261, 2009
Oral Communications:
  • Azithromycin is not able to decrease inflammatory process in cystic fibrosis human bronchial epithelial cells (2009) Saint-Criq V, Guillot L, Rebeyrol C, Corvol H, Jacquot J, Clement A, Tabary O 32nd European CF Conference, Brest, France
  • Azithromycin is not able to decrease inflammation process in cystic fibrosis bronchial cells (2008) Saint-Criq V, Le Rouzic P, Jacquot J, Clement A, Tabary O (2008) 2nd European CF Young Investigator Meeting. Lille, France
  • Azithromycin is not able to decrease inflammation process in cystic fibrosis bronchial cells (2008) Saint-Criq V, Jacquot J, Clement A, Tabary O 31th European Cystic Fibrosis Society conference, Prague, Czech Republic (published in Journal of Cystic Fibrosis, 7 (suppl.2): S52)

Posters:

  • Azithromycin fails to reduce inflammation in human cystic fibrosis bronchial epithelial cells (2009) Saint-Criq V, Guillot L, Rebeyrol C, Corvol H, Jacquot J, Clement A, Tabary O European Cystic Fibrosis Society Basic Science Conference, Tavira, Portugal
  • Azithromycin fails to reduce inflammation in human cystic fibrosis bronchial epithelial cells (2008) Saint-Criq V, Guillot L, Rebeyrol C, Corvol H, Jacquot J, Clement A, Tabary O10ème Colloque des jeunes Chercheurs de la Mucoviscidose, Paris, France
  • Azithromycin fails to reduce CF pulmonary inflammation (2008) Saint-Criq V, Jacquot J, Clement A, Tabary O 22nd Annual North American Cystic Fibrosis Conference, Orlando, USA
  • Azithromycin is not able to decrease inflammatory process in cystic fibrosis cells (2008) Saint-Criq V, Le Rouzic P, Jacquot J, Clement A, Tabary O 9ème Journées de l’École Doctorale de Physiopathologie et Physiopathologie, Paris, France
  • Azithromycin is not able to decrease inflammatory process in cystic fibrosis (2008) Saint-Criq V, Le Rouzic P, Jacquot J, Clement A, Tabary O 9ème Colloque des jeunes Chercheurs de la Mucoviscidose, Paris, France
  • Oxidative stress induces ERK1/2 MAP kinase but not NFκB activation in cystic fibrosis lung epithelial cells: potential mechanism for excessive IL8 secretion (2007) Boncoeur E, Saint-Criq V, Bonvin E, Roque T, Henrion-Caude A, Gruenert DC, Clement A, Jacquot J, Tabary O 3ème Séminaire du Centre de Recherche Saint-Antoine, Dourdan, France
  • Oxidative stress induces ERK1/2 MAP kinase but not NFB activation in cystic fibrosis lung epithelial cells: potential mechanism for excessive IL8 secretion (2007) Boncoeur E, Bonvin E, Saint-Criq V, Muselet-Charlier C, Gruenert DC, Clement A, Jacquot J, Tabary O 3ème Journées de Recherche Respiratoire, Paris, France (Revue des Maladies Respiratoires, 24(9): 1230)
  • Macrolides Effects on Molecular Mechanisms Involved in Inflammation of CF Cells (2007) Saint-Criq V, Bonvin E, Le Rouzic P, Jacquot J, Tabary O, Clement A 8ème Journées de l’Ecole Doctorale de Physiopathologie et Physiopathologie, Paris, France