Date: 12 July 2011

RCSI researchers; Heinrich Huber, Heiko Dussmann, Sean Kilbride, Markus Rehm and Jochen Prehn have conducted a study which reveals new insights into how cancer cells can maintain a resistance to chemotherapy. Their findings show that when cancer cells are exposed to elevated glucose levels, mitochondrial function can be restored and osmotic homeostasis can be maintained. The research was published in the scientific journal Molecular Systems Biology and featured in a number of online media outlets including Science Daily and News Medical. The research team was funded by NBIP Ireland, SFI, EU-FP7 and HRB.